Acute lymphangitis is most often caused by the bacterium Streptococcus pyogenes. This potentially dangerous bacterium also causes strep throat, infections of the heart, spinal cord, and lungs, and in the 1990s has been called the "flesh-eating bacterium." Staphylococci bacteria may also cause lymphangitis.
Although anyone can develop lymphangitis, some people are more at risk. People who have had radical mastectomy (removal of a breast and nearby lymph nodes), a leg vein removed for coronary bypass surgery, or recurrent lymphangitis caused by tinea pedis (a fungal infection on the foot) are at an increased risk for lymphangitis.
The characteristic symptoms of acute lymphangitis are the wide, red streaks which travel from the site of infection to the armpit or groin. The affected areas are red, swollen, and painful. Blistering of the affected skin may occur. The bacterial infection causes a fever of 100-104°F (38-40°C). In addition, a general ill feeling, muscle aches, headache, chills, and loss of appetite may be felt.